According to the Uganda Red Cross Society (URCS), several other cracks have developed in the area and communities have been warned.
A six-year-old boy has been killed by the Monday night landslides in Banarutere village, Bubyangu sub-county in Mbale district.
According to the Uganda Red Cross Society (URCS), three other family members were injured by the slides that left houses devastated.
"Three seriously injured: mother, father and grandmother to the deceased," a report by URCS spokesperson Irene Nakasiita said.
Red Cross officials led by the Mbale branch manager, Ayub Twaha, are on the ground assessing the situation.