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Israel bombarded Gaza and pressed its ground operations on Thursday after issuing what it called a "last warning" for Palestinians to return hostages and remove Hamas from power.
The renewed offensive shattered a relative calm that had pervaded since truce took hold mid-January.
Heavy air strikes began strafing Gaza early Tuesday, killing more than 400 people, according to the Hamas-run territory's health ministry.
Gaza rescuers said at least 10 more people were killed in a pre-dawn bombing near Khan Yunis Thursday.
On Wednesday, the Israeli military announced it had resumed ground operations "in the central and southern Gaza Strip to expand the security perimeter and create a partial buffer between the north and south".
As Israel defied calls from foreign governments to preserve the ceasefire, Gazans were left to once again comb through rubble to find the bodies of their loved ones.
"We're digging with our bare hands," said a man trying to dislodge a child's body from a heap of concrete in Gaza City.
After Israel urged civilians to leave areas it described as "combat zones", families with young children filled the roads leading out of northern Gaza.
Fred Oola, senior medical officer at the Red Cross field hospital in Rafah, said the renewed strikes shattered the relative calm of the past two months.
"Now, we can feel the panic in the air... and we can see the pain and devastation in the faces of those we are helping," he said.
Palestinians react near the bodies of the victims of Israeli overnight airstrikes in the northern Gaza Strip, at the Indonesian Hospital in Beit Lahia, on March 20, 2025.
Impasse
Hamas says it is willing to negotiate and has called on the international community to act to bring the war to an end.
An official from the group rejected, however, Israeli demands to renegotiate the three-stage deal agreed with Egyptian, Qatari and US mediators.
"Hamas has not closed the door on negotiations but we insist there is no need for new agreements," Taher al-Nunu told AFP.
Talks have stalled over how to proceed with the ceasefire, after the first phase expired in early March.
Israel and the United States have sought to change the terms of the deal by extending phase one.
Hamas wants negotiations for phase two, meant to establish a lasting ceasefire and an Israeli withdrawal from Gaza while the remaining hostages are exchanged for Palestinian prisoners.
"Moving to the second phase seems to be a non-option for Israel," said Ghassan Khatib, a political analyst and former Palestinian Authority minister.
"They don't like the second phase because it involves ending the war without necessarily achieving their objective of ending Hamas."
Israel and Washington have portrayed Hamas's rejection of a phase one extension as a refusal to release more hostages.
'Shattering' hopes
The renewed Israeli bombardment sent a stream of new casualties to the few hospitals still functioning in Gaza.
Israeli military tanks are positioned along Israel's southern border with the northern Gaza Strip on March 19, 2025.