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Ethel Kennedy, a tireless advocate for human rights and widow of assassinated US politician Robert F. Kennedy, died Thursday at the age of 96, her family said.
"It is with our hearts full of love that we announce the passing of our amazing grandmother," former congressman Joe Kennedy III said on social media.
Ethel Kennedy, who died of complications from a stroke, was a matriarch of a family that counted former president John F. Kennedy -- also assassinated -- and senator Ted Kennedy among its ranks.
Born Ethel Skakel in Chicago in 1928, she met her future husband at the age of 17.
Six months after his death, Ethel Kennedy gave birth to the couple's 11th child.
She went on to found Robert F. Kennedy Human Rights, an advocacy organization notable for its work on freedom of expression around the world.
She was also the mother of Robert F. Kennedy Jr, a vaccine conspiracy theorist whose failed third-party presidential bid and endorsement of Republican Donald Trump cast a shadow over the family's status in American politics and the Democratic Party.
Robert Kennedy -- known as Bobby or RFK -- would go on to serve as US attorney general in his brother John's administration and later as a senator representing New York.
Five years after JFK's assassination, Robert Kennedy was himself shot dead while running for president in 1968.
In 2014, then-president Barack Obama honored her with the Presidential Medal of Freedom, the highest civilian distinction in the United States.
Ethel Kennedy was awarded the Presidential Medal of Freedom by President Barack Obama at the White House East Room in November 2014. (AFP)