Jurgen Klopp is also without the injured Virgil van Dijk, Joe Gomez, Alex Oxlade-Chamberlain, Naby Keita, Xherdan Shaqiri, Trent Alexander-Arnold and James...
Already depleted by an injury crisis, the Reds will play three games in six-and-a-half days this week.
Melwood has been the club's base for more than 70 years, with generations of Anfield players honing their craft on the training pitches.
Paul Pogba remains a square peg in a round hole at Manchester United despite occasional flashes of brilliance.
Portugal forward Jota has made an instant impact since joined the English champions from Wolve.
The club would not say how long the 29-year-old central defender would be out.
Klopp's side are likely to be without Van Dijk for the rest of the season .
In recent seasons, Evertonians have dreaded this fixture.
"Sadio Mane has tested positive for Covid-19 and is currently self-isolating according to the necessary guidelines," Liverpool said in a statement.
Arteta's side were beaten 3-1 by the Reds in the league on Monday and they return to Anfield on Thursday for a League Cup fourth round tie.
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