PHOTO: Hepatitis B vaccines
Uganda is one of the few African countries that are making progress in the fight against hepatitis, the World Health Organisation has said.
In a statement released Tuesday, the WHO Africa office noted that the country had the political will to fund the fight against the deadly virus.
“In Uganda, where more than 6% of the population is infected, the commitment to end hepatitis infection was driven by civil society and strong political will with the result that it became one of the first African nations to fund domestic action against hepatitis B,” the statement said.
It added: “With investments of around $3 million a year, Uganda embarked on a massive, free hepatitis B screening programme in 2015, along with widespread community mobilisation and awareness-raising actions. More than four million people have been screened. More than 30% of the population who are infected with hepatitis B are now aware of their status and can access comprehensive treatment services, including free medication.”
“This performance exceeds the 2020 target for screening and awareness. There however remains much to be done to reach treatment targets,” the statement notes.
This development comes just as the country is hosting the 2019 African Hepatitis summit in the capital Kampala.
“It is fitting that the first African Hepatitis Summit should be held in Uganda,” says Dr. Matshidiso Moeti, WHO Regional Director for Africa.
“The country has superb lessons to share, and we support these important exchanges as they are helping to build evidence-based policies and promoting partnerships for more concerted action against viral hepatitis across the region. They are showing us that beating this disease is achievable.”
Hepatitis is a viral infection that causes inflammation of the liver. In humans it is caused by five different hepato-trophic viruses namely; Hepatitis A virus, Hepatitis B virus, Hepatitis C virus, Hepatitis D virus and Hepatitis E virus.
All Hepatitis viruses cause acute infections however Hepatitis D, Hepatitis C, and Hepatitis D frequently cause chronic infections. Chronic hepatitis may progress to cause liver cirrhosis and hepatocellular carcinoma thus accounting for most of the burden of disease in Uganda.
Uganda is highly endemic for Hepatitis B with a prevalence of 4.5% among adults 15-64 years old.
The Uganda Population-based HIV impact assessment 2016 survey indicates that chronic Hepatitis B infection prevalence varies across the country with the highest rates in Northern region with 4.6% in mid-North, 4.4% in North East and 3.8% in West Nile.
Hepatitis B infection was lower in the rest of the country with a range of 0.8% in the South West region to 2% in the Central region where Nakaseke district is located.
During the ongoing summit, a new scorecard – the first to examine hepatitis prevalence and response in the WHO African region, is expected to be released.
It shows which of the 47 countries are on track to eliminate the disease that affects one in 15 people in the region.
“This analysis is the first to track each country in the region and to assess progress towards the goal of saving the lives of more than two million Africans who may develop progressive hepatitis B or C liver disease in the next decade if countries fail to ramp up their efforts,” said Moeti.
It provides vital information about the status of the regional hepatitis response, measuring progress against the Framework for Action for the Prevention, Care and Treatment of Viral Hepatitis in the African Region (2016–2020).
The scorecard was created as a guide for member states on the implementation of the global health strategy on viral hepatitis, which calls for the elimination of hepatitis by 2030.
Every year, more than 200 000 people in Africa are dying from complications of viral hepatitis B and C-related liver disease, including cirrhosis and liver cancer.
Sixty million people in the WHO Africa Region were living with chronic hepatitis B infection in 2015. More than 4.8 million of them are children under five years old. A further 10 million are infected with hepatitis C, most likely due to unsafe injection practices within health facilities or by communities.
“The analysis shows that 28 countries have developed a national hepatitis strategic plan for viral hepatitis; however, most are still in draft form with only 13 officially published and disseminated,” the statement added.
WHO has been a major partner in the regional response with policy development and provision of technical and financial support as well as capacity building for a coordinated regional response.
Only 15% of countries are leading prevention efforts with national coverage of both Hepatitis B birth dose and childhood pentavalent vaccination exceeding 90%.
There are major gaps in hepatitis testing and treatment with less than eight countries providing subsidized testing and treatment for viral hepatitis.
Uganda has started free nationwide hepatitis B treatment, and Rwanda is providing free treatment for both hepatitis B and C, WHO statement says.
“These two countries are championing the regional response and are on track to reach the 2020 Framework targets for testing and community awareness,” it added.
Administration of the hepatitis B vaccination at birth and in early infancy is the most effective way to halt the transmission of the virus. This is because 95% of the burden of chronic disease is due to infections among children, acquired before their fifth birthday, including mother-to-child transmission.
In spite of the low cost of birth dose vaccination – less than US$ 0.20 per child – only 11 countries in the region are following this protocol. One such country is Cabo Verde where the government has mobilized financial resources and has achieved 99% vaccination coverage at birth.